ABSTRACT
Objective To explore the clinical value of virtual touch tissue quantification (VTQ) technique in the diagnosis of acute rejection of transplant kidney at different stages. Methods Clinical data of 170 renal transplant recipients were retrospectively analyzed. According to the time of VTQ examination and the occurrence of acute rejection after renal transplantation, the recipients within 4 weeks and after 4 weeks post-renal transplantation were assigned into the normal renal function group (n=41, 51) and acute rejection group (n=22, 56). Clinical ultrasound parameters at different stages after renal transplantation were compared between two groups. The diagnostic value of ultrasound parameters in acute rejection at different stages after renal transplantation was evaluated. Results Within 4 weeks post-renal transplantation, the resistance index (RI) and shear wave velocity (SWV) in the acute rejection group were significantly higher than those in the normal renal function group (both P < 0.001). After 4 weeks post-renal transplantation, the SWV in the acute rejection group was significantly higher than that in the normal renal function group (P < 0.001). The area under curve (AUC) of RI and SWV in the diagnosis of acute rejection were 0.729 and 0.803 respectively within 4 weeks post-renal transplantation, which were 0.478 and 0.794 respectively after 4 weeks post-renal transplantation. The diagnostic value of SWV was higher than RI (P < 0.05). The cutoff value of SWV in the diagnosis of acute rejection within 4 weeks post-renal transplantation was considerably higher than that after 4 weeks post-renal transplantation. Conclusions VTQ technique can effectively assist in diagnosing acute rejection of transplant kidney at different stages.
ABSTRACT
Objective: To compare the diagnostic value of virtual touch tissue quantification (VTQ) technique and virtual touch tissue imaging quantification (VTIQ) technique in benign and malignant breast masses with different sizes. Methods: Totally 219 breast masses were selected and confirmed by pathology. According to the largest diameter, all masses were divided into three groups: 5-10 mm (S1 group), 11-20 mm (S2 group) and 21-39 mm (S3 group). The shear wave velocity (SWV) value (SWVVTQ) was obtained by VTQ examination, the SWV maximum value (SWVmax) and SWVmax to the SWV of the surrounding gland in the same depth (SWVratio) were obtained by VTIQ examination before surgery. The pathological results were used as the criteria to compare the diagnostic value of two virtual touch tissue quantification techniques for benign and malignant breast masses of different sizes. Results: There were significant differences in SWVVTQ, SWVmax, SWVratio between the benign and malignant breast masses in 3 groups (all P0.90. The difference of AUC between SWVVTQ and SWVmax, SWVratio was statistically significant in S1 group (P0.05). Conclusion: For breast masses with the largest diameter >10 mm, the diagnostic value of VTQ and VTIQ techniques are equivalent. For breast masses with the largest diameter ≤10 mm, VTIQ technology has higher diagnostic value than VTQ technology in the diagnosis of benign and malignant breast masses.